March 2007 Last month my two daughters, Cara, aged 18, and Dominique, aged 21 visited their local GP for a follow-up consultation. Both had been diagnosed as having numerous primordial follicles (at least 15 bilaterally), suggesting the presence of polycystic ovaries. And both, for the past six months, have been incorporating transdermal progesterone cream as part of their treatment protocol. Ultrasound reports confirmed the girls’ ovaries had fully healed. But did the GP believe the evidence … that bioidentical progesterone replacement therapy actually worked in both cases? Well, no she didn’t. But before I get into that, let’s recap on how my girls came to be diagnosed with polycystic ovaries..