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When do I start the cream?

We are constantly learning about progesterone dosage and its usage. In summary, here are some simple guidelines we recommend:


  • Menopausal - start straight away, cream usage 3 weeks on, 1 week off.
  • Cyclic (regular periods, 28 day cycle) - start cream from day 12 to day 26, day 1 being first day of bleed.
  • Cyclic (regular periods, 30 day cycle) - start cream from day 14 to day 28, day 1 being first day of bleed.
  • Non Cyclic (no regular period is established) - start immediately, follow pattern 2 weeks on cream, 2 weeks off. This will mimic a cyclic pattern whether you are having a period or not. If a cyclic period emerges, adjust your breaks to fall into line when bleeding starts, resuming cream on day 12 - 26.
  • Elderly - start immediately, 5 day break each month or, if this is going to prove difficult such as in nursing homes, simply break from cream every weekend where possible.
  • Pregnancy - IF you commenced cream prior to becoming pregnant, DO NOT BREAK FROM CREAM. Any drop in progesterone levels may trigger a miscarriage. You can safely continue taking bioidentical progesterone cream throughout your pregnancy without fear of it interferring with your baby’s development.

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